|
|
|
UPCC 16412
|
A Phase 3, Randomized, Controlled, Open-label, Multicenter, Safety and Efficacy Study of Dexamethasone Plus MLN9708 or Physician's Choice of Treatment Administered to Patients With Relapsed or Refractory Systemic Light Chain (AL) Amyloidosis |
III |
Chemotherapy, Hormonal Therapy, Immunotherapy, Signal Transduction Inhibitor |
melphalan; thalidomide; cyclophosphamide; dexamethasone; lenalidomide; MLN9708 |
|
690
|
A Trial of Single Autologous Transplant With or Without Consolidation Therapy Versus Tandem Autologous Transplant With Lenalidomide Maintenance for Patients With Multiple Myeloma (BMT CTN 0702) |
III |
Bone Marrow Transplant / Stem Cell Transplant, Hormonal Therapy, Immunotherapy, Signal Transduction Inhibitor |
bortezomib; dexamethasone; lenalidomide |
|
UPCC 07409
|
Randomized Phase II Trial of CD3/CD28 Activated Id-KLH Primed Autologous Lymphocytes in Patients With Myeloma Undergoing Autologous Transplant |
II |
Immunotherapy |
Id-KLH |
|
CR100755
|
A Phase 2, Randomized, Blinded, Placebo-controlled, Multicenter Study of Siltuximab (Anti IL 6 Monoclonal Antibody) in Subjects With High-risk Smoldering Multiple Myeloma |
II |
Immunotherapy |
siltuximab |
|
UPCC 27412
|
A Phase I/II Study of the Tolerability of Lenalidomide and Low Dose Dexamethasone in Previously Treated Multiple Myeloma Patients With Impaired Renal Function |
I / II |
Hormonal Therapy, Immunotherapy |
dexamethasone; lenalidomide |
|
AMyC 10-MM-01
|
A Multi-Center Phase I/II, Open-Label, Dose-Finding Pilot Study of the Combination of Carfilzomib and Pomalidomide With Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma |
I / II |
Hormonal Therapy, Immunotherapy, Signal Transduction Inhibitor |
dexamethasone; carfilzomib; pomalidomide |
|
ACY-100
|
A Phase 1/2, Open-Label, Multicenter Study of ACY-1215 Administered Orally as Monotherapy and in Combination With Bortezomib and Dexamethasone for the Treatment of Relapsed or Relapsed/Refractory Multiple Myeloma |
I / II |
Hormonal Therapy, Signal Transduction Inhibitor |
bortezomib; dexamethasone; Rocilinostat |
|
UPCC 24412
|
A Phase I Dose Escalation Study to Investigate the Safety, Pharmacokinetics, Immunoregulatory Activity, and Preliminary Antitumor Activity of Anti-Programmed-Death 1 (PD-1) Antibody (BMS-936558) in Subjects With Relapsed or Refractory Hematologic Malignancy |
I |
Immunotherapy |
BMS-936558 |