|
|
|
715
|
A Multi-Center, Phase III, Randomized Trial of Reduced Intensity (RIC) Conditioning and Transplantation of Double Unrelated Umbilical Cord Blood (dUCB) Versus HLA-Haploidentical Related Bone Marrow (Haplo-BM) for Patients With Hematologic Malignancies (BMT CTN #1101) |
III |
Immunotherapy |
Not Applicable |
|
UPCC-29412
|
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of GS-1101 in Combination With Rituximab for Previously Treated Indolent Non-Hodgkin Lymphomas |
III |
Immunotherapy, Signal Transduction Inhibitor |
rituximab; Idelalisib |
|
UPCC-03712
|
Dose Optimization Trial of Autologous T Cells Engineered to Express Anti-CD19 Chimeric Antigen Receptor (CART-19) in Patients with Relapsed or Refractory CD19+ Chronic Lymphocytic Leukemia (CLL) |
II |
Immunotherapy |
CART 19 |
|
CR100956
|
An Open-label, Multicenter, Single-arm, Phase 2 Study of PCI-32765 (Ibrutinib) in Subjects With Refractory Follicular Lymphoma |
II |
Signal Transduction Inhibitor |
ibrutinib |
|
ECOG-E1A10
|
A Randomized Phase I/II Study of Bortezomib, Rituximab, Dexamethasone and Temsirolimus in Patients With Relapsed Waldenstrom's Macroglobulinemia and Relapsed/Refractory Mantle Cell, Follicular, Marginal Zone or Small Lymphocytic Lymphomas (Phase I), and Untreated/Relapsed Waldenstrom's Macroglobulinemia (Phase II) |
I / II |
Hormonal Therapy, Immunotherapy, Signal Transduction Inhibitor |
bortezomib; rituximab; dexamethasone; temsirolimus |
|
UPCC 11411
|
Maintenance Lenalidomide in Lymphoma |
I / II |
Immunotherapy |
lenalidomide |
|
UPCC 03411
|
A Phase I/IIa, Dose-Ranging Safety and Efficacy Study of Topical Resiquimod for the Treatment of Early Stage Cutaneous T Cell Lymphoma |
I / II |
Immunotherapy |
resiquimod |
|
813320
|
A Phase I/IIa, Dose-Ranging Safety and Efficacy Study of Topical Resiquimod for the Treatment of Early Stage Cutaneous T Cell Lymphoma |
I / II |
Immunotherapy |
resiquimod |
|
CHP959
|
Pilot Study of Redirected Autologous T Cells Engineered to Contain Anti-CD19 Attached to TCR and 4-1BB Signaling Domains in Patients With Chemotherapy Resistant or Refractory CD19+ Leukemia and Lymphoma |
I |
Immunotherapy |
CART 19 |
|
UPCC 04409
|
Pilot Study of Redirected Autologous Tcells Engineered to Contain Anti-CD19 Attached to TCR and 4-1BB Signaling Domains in Patient With Chemotherapy Resistant or Refractory CD19+ Leukemia and Lymphoma |
I |
Biological Therapy, Chemotherapy |
CD19CAR T-cells |
|
UPCC 24412
|
A Phase I Dose Escalation Study to Investigate the Safety, Pharmacokinetics, Immunoregulatory Activity, and Preliminary Antitumor Activity of Anti-Programmed-Death 1 (PD-1) Antibody (BMS-936558) in Subjects With Relapsed or Refractory Hematologic Malignancy |
I |
Immunotherapy |
BMS-936558 |
|
UPCC-18406
|
A Phase I Study of Bexxar® (Tositumomab and 131I-Tositumomab) Radioimmunotherapy in Patients With Relapsed or Residual CD20 Antigen-Expressing B-Cell Lymphomas Following Autologous Hematopoietic Stem Cell Transplantation |
I |
Bone Marrow Transplant / Stem Cell Transplant, Radiotherapy, Immunotherapy |
tositumomab |