|
|
|
TS-102
|
A Phase III Clinical Trial Evaluating TheraSphere® in Patients With Metastatic Colorectal Carcinoma of the Liver Who Have Failed First Line Chemotherapy |
III |
Radiotherapy |
Not Applicable |
|
UPCC 05209
|
A Phase II/Pharmacodynamic Study of Preoperative or Definitive FOLFOX Plus Bevacizumab, With the Additional Pharmacodynamic Goal of Assessing Tumor Blood Flow as Measured by Dynamic Contrast-enhanced MRI, and the Induction of Hypoxia and Apoptosis as Measured by PET in Patients With Rectal Cancer |
II |
Angiogenesis Inhibitor, Imaging Procedure |
bevacizumab |
|
Onconova 09-09
|
A Phase II Study of Oral Rigosertib in Patients With Relapsed or Metastatic, Platinum-resistant, Human Papillomavirus Positive or Negative Squamous Cell Carcinoma |
II |
Signal Transduction Inhibitor |
rigosertib |
|
GO28074
|
A Phase II, Multicenter, Open-Label, Randomized Study Evaluating the Efficacy and Safety of MEHD7945A + FOLFIRI Versus Cetuximab + FOLFIRI in Second Line in Patients With KRAS Wildtype Metastatic Colorectal Cancer |
II |
Chemotherapy, Immunotherapy (Monoclonal Antibody), EGFR Inhibitor, Topoisomerase Inhibitor |
fluorouracil; irinotecan; cetuximab; leucovorin ; MEHD7945A (RG7597) |
|
UPCC-07210
|
A Phase I/II Pharmacodynamic Study of Hydroxychloroquine in Combination With FOLFOX Plus Bevacizumab to Inhibit Autophagy in Colorectal Cancer |
I / II |
Angiogenesis Inhibitor, Chemotherapy, Other |
oxaliplatin; fluorouracil; bevacizumab; leucovorin ; hydroxychloroquine |
|
CLDE225A2112
|
A Phase Ib, Multi-center, Two Parallel Group, Open-label, Drug-drug Interaction Study to Assess the Effect of LDE225 on the Pharmacokinetics of Bupropion and Warfarin in Patients With Advanced Solid Tumors |
I |
Other |
warfarin; bupropion |
|
CA186-011
|
A Phase 1 Study of the Safety, Tolerability, Pharmacokinetics and Immunoregulatory Activity of BMS-663513 (Anti-CD137) in Subjects With Advanced and/or Metastatic Solid Tumors |
I |
Immunotherapy |
BMS-663513 |
|
UPCC - 13212
|
A Phase 1 Study of LY2801653 in Patients With Advanced Cancer |
I |
c-MET Inhibitor |
LY2801653 |