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Clinical Trials Listing
Active treatment trials at Penn's Abramson Cancer Center
Protocol ID Title Phase Modality Drug
SURG-073 A Randomized Controlled Trial of Perioperative Risk Stratification and Risk-based, Protocol-driven Management in Patients Undergoing Elective Major Cancer Surgery III Not Applicable
CCRRC 2007-32 A Randomized, Controlled Trial of Intraoperative Celiac Plexus Neurolysis for Patients With Operable (Resectable and Unresectable) Pancreatic and Periampullary Cancer III Supportive Care Not Applicable
1VIT14039 IRON CLAD: Can Iron Lessen Anemia Due to Cancer and Chemotherapy: A Multi-center, Randomized, Double-blinded, Controlled Study to Investigate the Efficacy and Safety of Injectafer® (Ferric Carboxymaltose Injection) III
ABI-007-PANC-003 A Phase 3, Multicenter, Open-label, Randomized Study of Nab-Paclitaxel Plus Gemcitabine Versus Gemcitabine Alone as Adjuvant Therapy in Subjects With Surgically Resected Pancreatic Adenocarcinoma III Chemotherapy gemcitabine; nab-paclitaxel
IMMU-107-04 An International, Multi-Center, Double-Blind, Randomized, Phase III Trial of 90Y-Clivatuzumab Tetraxetan Plus Low-Dose Gemcitabine Versus Placebo Plus Low-Dose Gemcitabine in Patients With Metastatic (Stage IV) Pancreatic Adenocarcinoma Who Received at Least Two Prior Treatments (PANCRIT-1) III Chemotherapy, Immunotherapy (Monoclonal Antibody) gemcitabine; 90Y-clivatuzumab tetraxetan
UPCC-05912 Extended Duration Varenicline for Smoking Among Cancer Patients: A Clinical Trial III Other, Supportive Care varenicline tartrate
AT005074 Long-Term Chamomile Therapy for Generalized Anxiety Disorder (GAD) III Supportive Care Not Applicable
RTOG-0848 A Phase III Trial Evaluating Both Erlotinib and Chemoradiation as Adjuvant Treatment for Patients With Resected Head of Pancreas Adenocarcinoma II / III Chemotherapy, Radiation Therapy, Signal Transduction Inhibitor gemcitabine; fluorouracil; capecitabine; erlotinib
11D.365 Phase II, Open Label Study of Intravenous Ascorbic Acid in Combination With Gemcitabine and Erlotinib in the Treatment of Metastatic Pancreatic Cancer II Chemotherapy, Other gemcitabine; erlotinib; ascorbic acid
UPCI 13-143 Phase II Study of Neoadjuvant Chemotheraphy (Gemcitabine and Nab-Paclitaxel vs. mFOLFIRINOX) and Sterotatic Body Radiation Therapy for Borderline Resectable Pancreatic Cancer II Chemotherapy oxaliplatin; gemcitabine; nab-paclitaxel
Jefferson Hypertonic Prospective Randomized Controlled Trial on the Use of a Restrictive Fluid Regimen With Hypertonic Saline for Patients Undergoing Pancreaticoduodenectomy II Prevention sodium chloride; lactated ringers
10-123 SBRT for Close or Positive Margins After Resection of Pancreatic Adenocarcinoma A Prospective Evaluation in Select Patients With Resected Pancreas Cancer II Radiation Therapy Not Applicable
UPCI# 13-074 Randomized Phase II Trial of Pre-Operative Gemcitabine and Nab Paclitacel With or With Out Hydroxychloroquine II Chemotherapy gemcitabine; nab-paclitaxel; hydroxychloroquine
UPCC-03213 A Randomized Phase II/Genomic Trial of Two Chemotherapy Regimens in Patients With Resected Pancreatic Adenocarcinoma II Radiation Therapy Not Applicable
RTOG 1201 A PHASE II RANDOMIZED TRIAL OF HIGH VERSUS STANDARD INTENSITY LOCAL OR SYSTEMIC THERAPY FOR UNRESECTABLE PANCREATIC CANCER II Chemotherapy, Complementary and Alternative Therapy, Radiation Therapy oxaliplatin; gemcitabine; fluorouracil; irinotecan; capecitabine; leucovorin
08-139 Induction Gemcitabine/Capecitabine Followed by SBRT in Pancreatic Adenocarcinoma A Prospective Evaluation in Patients With Locally Advanced Pancreas Cancer II Chemotherapy, Radiation Therapy gemcitabine; capecitabine
J1365 Phase 2 Study of MK-3475 in Patients With Microsatellite Unstable (MSI) Tumors II Immunotherapy (Monoclonal Antibody), Signal Transduction Inhibitor pembrolizumab
ML28897 My Pathway: An Open Label Phase IIa Study Evaluating Trastuzumab/Pertuzumab, Erlotinib, Vemurafenib, and Vismodegib in Patients Who Have Advanced Solid Tumors With Mutations or Gene Expression Abnormalities Predictive of Response to One of These Agents II Immunotherapy (Monoclonal Antibody), Signal Transduction Inhibitor trastuzumab; erlotinib; pertuzumab; vemurafenib; vismodegib
10-096 A Phase I/II Clinical Study of Vorinostat in Combination With Etoposide in Pediatric Patients < 21 Years at Diagnosis With Refractory Solid Tumors I / II Chemotherapy, Signal Transduction Inhibitor etoposide; vorinostat
C32496/1105 An Open-Label, Phase 1/Phase 2, Single-Agent Study of CEP-32496 in Patients With Advanced Solid Tumors in Phase 1 and in Patients With Advanced Melanoma and Metastatic Colorectal Cancer With BRAF Mutation in Phase 2 I / II Signal Transduction Inhibitor
12-110 A Phase 1/2 Trial Evaluating aDC1 Vaccines Combined With Tumor-Selective Chemokine Modulation as Adjuvant Therapy After Surgical Resection of Peritoneal Surface Malignancies I / II Immunotherapy, Signal Transduction Inhibitor celecoxib; interferon alfa-2b; rintatolimod; aDC1 vaccine
UPCC-19211 A Phase I/II/Pharmacodynamic Study of Hydroxychloroquine in Combination With Gemcitabine/Abraxane to Inhibit Autophagy in Pancreatic Cancer I / II Chemotherapy gemcitabine; nab-paclitaxel; hydroxychloroquine
CD-ON-MEDI4736-1108 A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MEDI4736 in Subjects With Advanced Solid Tumors I / II Immunotherapy (Monoclonal Antibody)
09-051 A Phase I Study of Stereotactic Body Radiation Therapy (SBRT) for Liver Metastases I Radiation Therapy Not Applicable
UPCI-10-115 An Early Phase 1 Study of ABT-888 in Combination With Carboplatin and Paclitaxel in Patients With Hepatic or Renal Dysfunction and Solid Tumors I Chemotherapy, PARP Inhibitor carboplatin; paclitaxel; veliparib
CD-ON-MEDI3617-1043 A Phase 1, Multicenter, Open-Label, Dose-Escalation and Expansion Study to Evaluate the Safety and Antitumor Activity of MEDI3617, a Fully Human Monoclonal Antibody Directed Against ANG2, in Adult Subjects With Advanced Solid Tumors I Immunotherapy (Monoclonal Antibody)
110060 A Phase I Pharmacokinetic Study of Belinostat for Solid Tumors and Lymphomas in Patients With Varying Degrees of Hepatic Dysfunction I Signal Transduction Inhibitor belinostat
C28001 An Open-Label, Phase 1, Dose Escalation Study of MLN2480 in Patients With Relapsed or Refractory Solid Tumors Followed by a Dose Expansion Phase in Patients With Metastatic Melanoma I Signal Transduction Inhibitor
120066 Phase I Trial of Oral 5-Fluoro-2-Deoxycytidine With Oral Tetrahydrouridine in Patients With Advanced Solid Tumors I Signal Transduction Inhibitor 5-fluoro-2-deoxycytidine; tetrahydrouridine
12-046 RT-054: A Phase I Study of Neoadjuvant Hypofractionated Chemoradiation Plus Radiosurgical Boost for Patients With Borderline Resectable and Locally Advanced Unresectable Pancreatic Cancer I Chemotherapy, Radiation Therapy gemcitabine
11-091 PHASE I STUDY OF FRACTIONATED STEREOTACTIC RADIOSURGERY FOR LARGE BRAIN METASTASES I Radiation Therapy Not Applicable
OER-RT-042 Phase I Study of Pulsed Low Dose Rate Reirradiation Delivered With 3DCRT/IMRT I Radiation Therapy Not Applicable
IMGN853-0401 A Phase 1, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of IMGN853 in Adults With Ovarian Cancer and Other FOLR1-Positive Solid Tumors I Immunotherapy (Monoclonal Antibody)
UPCC 32213 A Phase I Dual Dose Escalation Study of Radiation and Nab-Paclitaxel in Patients With Unresectable and Borderline Resectable Pancreatic Cancer I Chemotherapy, Radiation Therapy gemcitabine; nab-paclitaxel
UPCC 08913 A Pilot and Feasibility Study of Intraoperative Imagery of Solid Tumors With Indocyanine Green I Imaging Procedure Indocyanine Green
UPCC 27914 A Phase 1 First-in-Human Dose Study of LY3023414 in Patients With Advanced Cancer I Biological Therapy, Chemotherapy, Hormonal Therapy letrozole; midazolam;
UPCC-13213 A Phase 1B Study of the Safety and Tolerability of INCB039110 in Combination With Gemcitabine and Nab-Paclitaxel in Subjects With Advanced Solid Tumors I Chemotherapy gemcitabine; nab-paclitaxel; INCB039110
UPCC 31213 Phase I Study of Chimeric Antigen Receptor Modified T Cells in Patients With Mesothelin Expressing Cancers I Immunotherapy CART-meso
C28002 A Multiarm, Open-label, Phase 1b Study of MLN2480 (an Oral A-, B-, and CRAF Inhibitor) in Combination With MLN0128 (an Oral mTORC 1/2 Inhibitor), or Alisertib (an Oral Aurora A Kinase Inhibitor), or Paclitaxel, in Adult Patients With Advanced Nonhematologic Malignancies I Chemotherapy, Signal Transduction Inhibitor paclitaxel; alisertib; ;
PV-10-LC-01 A Phase 1 Study to Assess the Safety, Tolerability and Pharmacokinetics of PV-10 Chemoablation of Cancer Metastatic to the Liver or Recurrent Hepatocellular Carcinoma I Chemotherapy PV-10
UPCC 22913 Phase I Study of TERT DNA and Electroporation With and Without IL-12 DNA for Patients With Breast, Lung, or Pancreatic Cancer at High Risk of Relapse Post Definitive Surgery and Adjuvant Therapy I Immunotherapy Interleukin 12 (IL-12); INO-1400
UPCC 25914 Pilot Trial of HER-2/Neu Pulsed DC1 Vaccine for Patients With HER-2 Positive I Immunotherapy (Vaccine) HER-2 pulsed DC1 vaccine
UPCC 30914 Choosing Options for Insomnia in Cancer Effectively (CHOICE): A Comparative Effectiveness Trial of Acupuncture and Cognitive Behavior Therapy 0 Complementary and Alternative Therapy Not Applicable
13C.628 Generation of Patient Derived Pancreatic Cancer Cell Lines to Determine Mechanisms of Chemoresistance Not Specified Not Applicable
NCT01295658 Cancer Experience Registry Not Specified Not Applicable
14D.272 Use of a Brief Mindful Meditation Practice in Adult Cancer Patients Receiving Radiation Therapy Not Specified Not Applicable
STUDY00000378 The Value of Integrating Visual Arts (VIVA): Evaluating the Benefits of Hospital Room Artwork on Inpatient Wellbeing Not Specified Not Applicable
UPCC 23213 A Randomized Pilot/Pharmacodynamic/Genomic Study of Neoadjuvant Paricalcitol to Target the Microenvironment in Resectable Pancreatic Cancer Not Specified Hormonal Therapy paricalcitol
UPCC 14213 A Pilot Study to Evaluate Radiotherapy-Induced Ant-Tumor Immunity in Metastatic Carcinoma of the Pancreas Not Specified Radiation Therapy Not Applicable
PRO00000367 A Low-Carbohydrate Diet for Advanced or Metastatic Cancer Not Specified Other Not Applicable
UPCC-12807 Assessing Fertility Potential in Female Cancer Survivors Not Specified Imaging Procedure, Blood or Tissue Collection Not Applicable
Active non-treatment trials at Penn's Abramson Cancer Center
Protocol ID Title Phase Modality Drug

Sorry, your search did not return any Penn Non-Treatment Trials trials

Active advanced solid tumor trials at Penn's Abramson Cancer Center
Protocol ID Title Phase Modality Drug

Sorry, your search did not return any Phase 1: Solid Tumor Trials trials

Active proton therapy trials at Penn's Abramson Cancer Center
Protocol ID Title Phase Modality Drug

Sorry, your search did not return any Proton Therapy Trials trials

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