|
|
|
CALGB-30610
|
Phase III Comparison of Thoracic Radiotherapy Regimens in Patients With Limited Small Cell Lung Cancer Also Receiving Cisplatin and Etoposide |
III |
Radiotherapy |
Not Applicable |
|
ECOG-E1505
|
A Phase III Randomized Trial of Adjuvant Chemotherapy With or Without Bevacizumab for Patients With Completely Resected Stage IB (> 4cm)-IIIA Non-Small Lung Cancer (NSCLC) |
III |
Angiogenesis Inhibitor, Chemotherapy |
docetaxel; pemetrexed; carboplatin; cisplatin; gemcitabine; vinorelbine; bevacizumab; paclitaxel |
|
SWOG-S0819
|
A Randomized, Phase III Study Comparing Carboplatin/Paclitaxel or Carboplatin/Paclitaxel/Bevacizumab With or Without Concurrent Cetuximab in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) |
III |
Angiogenesis Inhibitor, Chemotherapy |
carboplatin; bevacizumab; cetuximab; paclitaxel |
|
MO22097
|
An Open-label, Randomized, Phase IIIb Trial Evaluating the Efficacy and Safety of Standard of Care +/- Continuous Bevacizumab Treatment Beyond Progression of Disease (PD) in Patients With Advanced Non-squamous Non-small Cell Lung Cancer (NSCLC) After First (1st)-Line Treatment With Bevacizumab Plus a Platinum Doublet-containing Chemotherapy |
III |
Angiogenesis Inhibitor |
bevacizumab |
|
OAM4971g
|
A Randomized, Phase III, Multicenter, Double-Blind, Placebo-Controlled Study Evaluating Efficacy and Safety of Onartuzumab (Metmab) in Combination With Tarceva (Erlotinib) in Patients With Met Diagnostic-Positive Non-Small Cell Lung Cancer Who Have Received Standard Chemotherapy for Advanced/Metastatic Disease |
III |
Immunotherapy (Monoclonal Antibody), EGFR Inhibitor |
erlotinib; onartuzumab |
|
PX-866-002
|
Phase 1/2 Study of PX-866 and Docetaxel in Patients With Solid Tumors |
II |
Chemotherapy, Signal Transduction Inhibitor |
docetaxel; PX-866 |
|
UPCC 18512
|
Phase 2 Study of Etirinotecan Pegol (NKTR-102) in the Treatment of Patients With Metastatic and Recurrent Non-Small Cell Lung Cancer (NSCLC) After Failure of 2nd Line Treatment |
II |
Chemotherapy |
NKTR-102 |
|
ECOG-E3508
|
A Phase II Randomized Trial of Paclitaxel, Carboplatin, Bevacizumab With or Without IMC-A12 in Patients With Advanced Non-Squamous Non- Small Cell Lung Cancer |
II |
Biological Therapy, Chemotherapy, Signal Transduction Inhibitor |
carboplatin; bevacizumab; paclitaxel; cixutumumab |
|
UPCC 27312
|
A Randomized, Double-Blind, Phase 2, Dose-Ranging Study to Evaluate the Safety and Efficacy of Veliparib and Whole Brain Radiation Therapy Versus Placebo and Whole Brain Radiation Therapy in Subjects With Brain Metastases From Non-Small Cell Lung Cancer |
II |
Radiotherapy, Signal Transduction Inhibitor |
veliparib |
|
CDR0000736704
|
Phase I and Randomized Phase II Double Blind Clinical Trial of Cisplatin and Etoposide in Combination With Veliparib (ABT-888) or Placebo as Frontline Therapy for Extensive Stage Small Cell Lung Cancer |
I / II |
Chemotherapy, Signal Transduction Inhibitor |
cisplatin; etoposide; veliparib |
|
AP26113-11-101
|
A Phase 1/2 Study of the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-Tumor Activity of the Oral ALK/EGFR Inhibitor AP26113 |
I / II |
Signal Transduction Inhibitor |
AP26113 |
|
UPCC 25508
|
Feasibility and PhaseI/II Trial of Preoperative Proton Beam Radiotherapy With Concurrent Chemotherapy for Resectable Stage IIIA or Superior Sulcus NSCLC |
I / II |
Chemotherapy, Proton Therapy |
cisplatin; etoposide |
|
UPCC 01510
|
Phase I Dose Escalation Trial of Proton Beam Radiotherapy With Concurrent Chemotherapy and Nelfinavir for Inoperable Stage III NSCLC |
I |
Chemotherapy, Proton Therapy |
carboplatin; cisplatin; etoposide; paclitaxel; nelfinavir mesylate |
|
P07990
|
Phase I Study of Single Agent MK-3475 in Patients With Progressive Locally Advanced or Metastatic Carcinoma, Melanoma, and Non-Small Cell Lung Carcinoma |
I |
Signal Transduction Inhibitor |
MK-3475 (Immunotherapy : PD-1 inhibitor) |
|
CA186-011
|
A Phase 1 Study of the Safety, Tolerability, Pharmacokinetics and Immunoregulatory Activity of BMS-663513 (Anti-CD137) in Subjects With Advanced and/or Metastatic Solid Tumors |
I |
Immunotherapy |
BMS-663513 |