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Clinical Trials Listing
Active treatment trials at Penn's Abramson Cancer Center
Protocol ID Title Phase Modality Drug
SURG-073 A Randomized Controlled Trial of Perioperative Risk Stratification and Risk-based, Protocol-driven Management in Patients Undergoing Elective Major Cancer Surgery III Not Applicable
1VIT14039 IRON CLAD: Can Iron Lessen Anemia Due to Cancer and Chemotherapy: A Multi-center, Randomized, Double-blinded, Controlled Study to Investigate the Efficacy and Safety of Injectafer® (Ferric Carboxymaltose Injection) III
PIN-PHO1201 Multicenter, Open-label, Randomized, Controlled Phase III Clinical Study of the Efficacy and Safety of Photodynamic Therapy Using Porfimer Sodium for Injection as Treatment for Unresectable Advanced Perihilar Cholangiocarcinoma III Chemotherapy cisplatin; gemcitabine
UPCC 34212 A Phase 3, Randomized, Double-Blind Study of Tivantinib (ARQ 197) in Subjects With MET Diagnostic-High Inoperable Hepatocellular Carcinoma Treated With One Prior Systemic Therapy III Signal Transduction Inhibitor tivantinib
UPCC-05912 Extended Duration Varenicline for Smoking Among Cancer Patients: A Clinical Trial III Other, Supportive Care varenicline tartrate
AT005074 Long-Term Chamomile Therapy for Generalized Anxiety Disorder (GAD) III Supportive Care Not Applicable
ML28897 My Pathway: An Open Label Phase IIa Study Evaluating Trastuzumab/Pertuzumab, Erlotinib, Vemurafenib, and Vismodegib in Patients Who Have Advanced Solid Tumors With Mutations or Gene Expression Abnormalities Predictive of Response to One of These Agents II Immunotherapy (Monoclonal Antibody), Signal Transduction Inhibitor trastuzumab; erlotinib; pertuzumab; vemurafenib; vismodegib
J1365 Phase 2 Study of MK-3475 in Patients With Microsatellite Unstable (MSI) Tumors II Immunotherapy (Monoclonal Antibody), Signal Transduction Inhibitor pembrolizumab
13-100 A Phase 2 Trial of Regorafenib as A Single Agent in Advanced and Metastatic Biliary Tract Carcinoma/Cholangiocarcinoma Patients Who Have Failed First-line Chemotherapy II Signal Transduction Inhibitor regorafenib
UPCC 18214 A Multi-Institutional, Single Arm, Two-Stage Phase II Trial of Nab-Paclitaxel and Gemcitabine for First-Line Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma II Chemotherapy gemcitabine; nab-paclitaxel
11-003311 A Phase II Randomized Multicenter Placebo-Controlled Blinded Study of Sorafenib Adjuvant Therapy in High Risk Orthotopic Liver Transplant (OLT) Recipients With Hepatocellular Carcinoma (HCC) II Signal Transduction Inhibitor sorafenib
C32496/1105 An Open-Label, Phase 1/Phase 2, Single-Agent Study of CEP-32496 in Patients With Advanced Solid Tumors in Phase 1 and in Patients With Advanced Melanoma and Metastatic Colorectal Cancer With BRAF Mutation in Phase 2 I / II Signal Transduction Inhibitor
12D.424 Phase I/II Study of Intravenous Ascorbic Acid in Treatment of Metastatic Hepatocellular Carcinoma I / II Other, Signal Transduction Inhibitor sorafenib; ascorbic acid
10-096 A Phase I/II Clinical Study of Vorinostat in Combination With Etoposide in Pediatric Patients < 21 Years at Diagnosis With Refractory Solid Tumors I / II Chemotherapy, Signal Transduction Inhibitor etoposide; vorinostat
UPCC 22213 Phase I-II Clinical Trial of the Safety and Preliminary Efficacy of Hydroxychloroquine Combined With Transarterial Chemoembolization in Unresectable Hepatocellular Carcinoma I / II Chemotherapy hydroxychloroquine
CD-ON-MEDI4736-1108 A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MEDI4736 in Subjects With Advanced Solid Tumors I / II Immunotherapy (Monoclonal Antibody)
UPCI-10-115 An Early Phase 1 Study of ABT-888 in Combination With Carboplatin and Paclitaxel in Patients With Hepatic or Renal Dysfunction and Solid Tumors I Chemotherapy, PARP Inhibitor carboplatin; paclitaxel; veliparib
C28001 An Open-Label, Phase 1, Dose Escalation Study of MLN2480 in Patients With Relapsed or Refractory Solid Tumors Followed by a Dose Expansion Phase in Patients With Metastatic Melanoma I Signal Transduction Inhibitor
110060 A Phase I Pharmacokinetic Study of Belinostat for Solid Tumors and Lymphomas in Patients With Varying Degrees of Hepatic Dysfunction I Signal Transduction Inhibitor belinostat
09-051 A Phase I Study of Stereotactic Body Radiation Therapy (SBRT) for Liver Metastases I Radiation Therapy Not Applicable
OER-RT-042 Phase I Study of Pulsed Low Dose Rate Reirradiation Delivered With 3DCRT/IMRT I Radiation Therapy Not Applicable
120066 Phase I Trial of Oral 5-Fluoro-2-Deoxycytidine With Oral Tetrahydrouridine in Patients With Advanced Solid Tumors I Signal Transduction Inhibitor 5-fluoro-2-deoxycytidine; tetrahydrouridine
265-101 Open-Label Dose-Escalation Trial to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Daily Oral MGCD265 Administered Without Interruption to Subjects With Advanced Malignancies I Biological Therapy, Signal Transduction Inhibitor
11-091 PHASE I STUDY OF FRACTIONATED STEREOTACTIC RADIOSURGERY FOR LARGE BRAIN METASTASES I Radiation Therapy Not Applicable
54F28-004 A Phase 1b Dose Escalation Study of OMP-54F28 in Combination With Sorafenib in Patients With Hepatocellular Cancer I Immunotherapy, Signal Transduction Inhibitor sorafenib;
UPCC 07913 A Phase 1b, Open-Label, Dose Escalation, Multi-arm Study of MLN4924 Plus Docetaxel, Gemcitabine, or Combination of Carboplatin and Paclitaxel in Patients With Solid Tumors I Chemotherapy, Signal Transduction Inhibitor docetaxel; carboplatin; gemcitabine; paclitaxel;
UPCC 08913 A Pilot and Feasibility Study of Intraoperative Imagery of Solid Tumors With Indocyanine Green I Imaging Procedure Indocyanine Green
UPCC 27914 A Phase 1 First-in-Human Dose Study of LY3023414 in Patients With Advanced Cancer I Biological Therapy, Chemotherapy, Hormonal Therapy letrozole; midazolam;
13008 A Phase 1 Study of LY2801653 in Patients With Advanced Cancer I Chemotherapy, Immunotherapy (Monoclonal Antibody), Signal Transduction Inhibitor cisplatin; cetuximab;
IMGN853-0401 A Phase 1, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of IMGN853 in Adults With Ovarian Cancer and Other FOLR1-Positive Solid Tumors I Immunotherapy (Monoclonal Antibody)
CD-ON-MEDI3617-1043 A Phase 1, Multicenter, Open-Label, Dose-Escalation and Expansion Study to Evaluate the Safety and Antitumor Activity of MEDI3617, a Fully Human Monoclonal Antibody Directed Against ANG2, in Adult Subjects With Advanced Solid Tumors I Immunotherapy (Monoclonal Antibody)
C28002 A Multiarm, Open-label, Phase 1b Study of MLN2480 (an Oral A-, B-, and CRAF Inhibitor) in Combination With MLN0128 (an Oral mTORC 1/2 Inhibitor), or Alisertib (an Oral Aurora A Kinase Inhibitor), or Paclitaxel, in Adult Patients With Advanced Nonhematologic Malignancies I Chemotherapy, Signal Transduction Inhibitor paclitaxel; alisertib; ;
PV-10-LC-01 A Phase 1 Study to Assess the Safety, Tolerability and Pharmacokinetics of PV-10 Chemoablation of Cancer Metastatic to the Liver or Recurrent Hepatocellular Carcinoma I Chemotherapy PV-10
UPCC 30914 Choosing Options for Insomnia in Cancer Effectively (CHOICE): A Comparative Effectiveness Trial of Acupuncture and Cognitive Behavior Therapy 0 Complementary and Alternative Therapy Not Applicable
UPCC-16213 A Pilot Trial of Transarterial Chemoembolization With or Without Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma Patients Awaiting Liver Transplantation 0 Radiation Therapy Not Applicable
NCT01295658 Cancer Experience Registry Not Specified Not Applicable
STUDY00000378 The Value of Integrating Visual Arts (VIVA): Evaluating the Benefits of Hospital Room Artwork on Inpatient Wellbeing Not Specified Not Applicable
14D.272 Use of a Brief Mindful Meditation Practice in Adult Cancer Patients Receiving Radiation Therapy Not Specified Not Applicable
PRO00000367 A Low-Carbohydrate Diet for Advanced or Metastatic Cancer Not Specified Other Not Applicable
A2ALL Core Protocol A2ALL: Adult-to-Adult Living Transplant Cohort Study Not Specified Other Not Applicable
UPCC-12807 Assessing Fertility Potential in Female Cancer Survivors Not Specified Imaging Procedure, Blood or Tissue Collection Not Applicable
07D.366 A Humanitarian Device Exemption Treatment Protocol of Therasphere for the Treatment of Unresectable Hepatocellular Carcinoma Not Specified Radiation Therapy Not Applicable
Active non-treatment trials at Penn's Abramson Cancer Center
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Active advanced solid tumor trials at Penn's Abramson Cancer Center
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Active proton therapy trials at Penn's Abramson Cancer Center
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