|
|
|
JWCI-MORD-LM/SL-CLND-1102
|
A Phase III Multicenter Randomized Trial of Sentinel Lymphadenectomy and Complete Lymph Node Dissection Versus Sentinel Lymphadenectomy Alone in Cutaneous Melanoma Patients With Molecular or Histopathological Evidence of Metastases in the Sentinel Node |
III |
Surgery |
Not Applicable |
|
GO27826
|
A Phase III, Randomized, Double-Blind, Placebo-Controlled Study of Vemurafenib (RO5185426) Adjuvant Therapy in Patients With Surgically Resected, Cutaneous BRAF Mutant Melanoma at High Risk for Recurrence |
III |
B-Raf Inhibitor |
vemurafenib |
|
ECOG-E1609
|
A Phase III Randomized Study of Adjuvant Ipilimumab Anti-CTLA4 Therapy Versus High-Dose Interferon Alpha-2b for Resected High-Risk Melanoma |
III |
Immunotherapy |
interferon alfa-2b; ipilimumab |
|
UPCC 11612
|
Randomized, Phase II Study of MK-3475 Versus Chemotherapy in Patients With Advanced Melanoma |
II |
Chemotherapy, Immunotherapy (Monoclonal Antibody) |
MK-3475 (Immunotherapy : PD-1 inhibitor) |
|
CA209-064
|
An Open-Label, Randomized, Phase 2 Study of Nivolumab Given Sequentially With Ipilimumab in Subjects With Advanced or Metastatic Melanoma |
II |
Immunotherapy |
ipilimumab |
|
UPCC 06611
|
RADVAX: A Stratified Phase I/II Dose Escalation Trial of Stereotactic Body Radiotherapy Followed by Ipilimumab in Metastatic Melanoma |
I / II |
Immunotherapy |
ipilimumab |
|
INCB 24360-201
|
A Phase 1/2 Randomized, Blinded, Placebo Controlled Study of Ipilimumab in Combination With INCB024360 or Placebo in Subjects With Unresectable or Metastatic Melanoma |
I / II |
Immunotherapy, Signal Transduction Inhibitor |
ipilimumab; INCB024360 |
|
PX-866-007
|
Phase 1/2 Study of PI-3K Inhibition With PX-866 Combined With Vemurafenib (BRAF Inhibitor) in Patients With BRAF-mutant Cancer Including Advanced Melanoma |
I / II |
Signal Transduction Inhibitor |
vemurafenib; PX-866 |
|
P07990
|
Phase I Study of Single Agent MK-3475 in Patients With Progressive Locally Advanced or Metastatic Carcinoma, Melanoma, and Non-Small Cell Lung Carcinoma |
I |
Signal Transduction Inhibitor |
MK-3475 (Immunotherapy : PD-1 inhibitor) |
|
CA186-011
|
A Phase 1 Study of the Safety, Tolerability, Pharmacokinetics and Immunoregulatory Activity of BMS-663513 (Anti-CD137) in Subjects With Advanced and/or Metastatic Solid Tumors |
I |
Immunotherapy |
BMS-663513 |
|
UPCC-05609
|
A Phase 1 Dose-Escalation Trial To Evaluate Safety, Tolerability And Immune Pharmacodynamics Of Combined Administration Of Tremelimumab (Blocking Anti-CTLA-4 Antibody) And CP-870,893 (Agonist Anti-CD40 Antibody) In Patients With Metastatic Melanoma |
I |
Biological Therapy, Immunotherapy |
tremelimumab; CP-870,893 |